The 4-0 Bills are seeking their 15th straight victory at home against the 2-2 Patriots in a battle between the AFC East’s best teams on Sunday Night Football. Buffalo has started the season with four straight 30+ point performances and looks to continue their homefield dominance before hitting the road for the rest of October.

The Buffalo Bills kick off the 2025 regular season and Highmark Stadiums’ Farewell Season, with a Sunday Night Football clash with the Baltimore Ravens. This preview will cover the key storylines, injury news, matchups to watch, x-factors, and my keys to victory and prediction.