The 7-3 Buffalo Bills travel to face the 5-5 Houston Texans on Thursday Night Football in a pivotal AFC showdown. Buffalo looks to earn a second straight win and keep pace in the AFC playoff race, while Houston aims to climb back above .500 and strengthen its postseason hopes.

The 6-3 Buffalo Bills host the 6-3 Tampa Bay Buccaneers in a pivotal Week 11 matchup at Highmark Stadium. Both teams look to rebound from last week’s losses and keep pace in the AFC and NFC playoff picture.

The 5-2 Buffalo Bills host the 5-3 Kansas City Chiefs in a marquee Week 9 matchup this Sunday at Highmark Stadium. Both teams enter the game looking to make a statement in the AFC race — with playoff implications already starting to take shape.

Fresh off their bye, the 4-2 Bills head to Charlotte to face the 4-3 Carolina Panthers. Buffalo is looking to avoid their 3rd straight loss while the Panthers are seeking their 4th straight win. Andy Dalton gets the start for an injured Bryce Young, and the Bills have three players making their 2025 debuts.

Coming off their first loss of the season, the 4-1 Bills head to Atlanta to face the 2-2 Falcons fresh off their bye week. Buffalo looks to return to their winning ways and maintain their position at the top of the AFC East and keep pace with the Indianapolis Colts in the battle for the AFC’s one seed.

The 4-0 Bills are seeking their 15th straight victory at home against the 2-2 Patriots in a battle between the AFC East’s best teams on Sunday Night Football. Buffalo has started the season with four straight 30+ point performances and looks to continue their homefield dominance before hitting the road for the rest of October.

The 3-0 Bills are seeking their 14th straight victory at home against the 0-3 Saints in their last home 1:00 PM game until November. Buffalo has started the season with three straight 30+ point performances for the second year in a row and look to continue their home field dominance against first year head coach Kellen Moore.

The 2-0 Buffalo Bills return to Orchard Park for a Thursday Night Football matchup with their division rival, the Miami Dolphins. Miami is looking to bounce back from its disastrous start to the season and avoid a 0-3 hole. The Bills are looking to win their seventh straight matchup over the Fins.

The Buffalo Bills fresh off their Sunday Night Football comeback over the Ravens travel to New Jersey for an AFC East battle with the 0-1 New York Jets. Can Josh Allen keep his hot streak going and make it four consecutive victories versus the division rival?

The Buffalo Bills kick off the 2025 regular season and Highmark Stadiums’ Farewell Season, with a Sunday Night Football clash with the Baltimore Ravens. This preview will cover the key storylines, injury news, matchups to watch, x-factors, and my keys to victory and prediction.

The NFL schedule was released two weeks ago. Yes, I am late on publishing this one, and the Buffalo Bills will start the season on Sunday Night Football in a rematch of their playoff game against the Baltimore Ravens. Buffalo’s strength of schedule ranks 5th easiest in 2025, based on total win percentage, and is the only team in the NFL that is currently the favorite in all 17 games.

The Buffalo Bills lose their regular season finale 23-16 to the New England Patriots. The victory, accompanied with Browns, Giants, and Titans losses, knocks the Patriots from the first overall pick in the 2025 NFL draft to the fourth. Buffalo didn’t seem to mind helping New England edge out the victory and prevent them from securing the top pick. In that regard, it was a strange game, so this will be a much different recap than most.

The 13-3 Buffalo Bills head to Foxboro for their last game of the regular season against the 3-13 New England Patriots. The Bills narrowly defeated New England two weeks ago, 24-21. This matchup will look a bit different as the Bills are planning to rest starters, with Josh Allen starting to continue his NFL-leading starts streak.

The Buffalo Bills beat the New York Jets 40-14 to finish the regular season undefeated at home while securing their position as the AFC’s number two seed heading into the playoffs. The Jets had three possessions in the first half that resulted in a turnover on downs, an interception, and a safety, allowing Buffalo to take a 12-0 lead into halftime. Buffalo scored 28 straight points in the second half to make it 40-0 before pulling their starters. Tyrod Taylor led two late scoring drives for the Jets.

The 12-3 Buffalo Bills welcome the 4-11 Jets to New York for their second matchup of the season. Both teams have gone down different paths since their week six meeting, with the Bills going 8-1 since then and the Jets going 2-7. A victory on Sunday would secure the two seed and cap off Buffalo’s first undefeated record at home since the 1990 season.

The Buffalo Bills survived a slow start against a resilient New England Patriots team to win 24-21 and move to 12-3 on the year. Drake Maye led the Patriots on back-to-back scoring drives to start the game and build a 14-0 lead. Buffalo fought back with 24 unanswered points, assisted by an improved second-half defensive effort that forced three turnovers.

The Buffalo Bills return home after their victory over the Detroit Lions to face the 3-11 New England Patriots. This is the first of two matchups over the final three weeks of the season for the AFC East rivals. With the two teams heading in different directions, Buffalo needs to keep its focus and continue its solid play for the remainder of the season. New England wants something positive to end a disappointing season under first-year head coach Jerod Mayo.

The Buffalo Bills knocked off the Detroit Lions 48-42, ending their 11-game winning streak. Buffalo never trailed in the game, with scores on their first three drives before heading into halftime up 21-14. The second half saw two punts and 55 combined points scored. The Bills capitalized on a fumble that allowed them to stretch their lead to 35-14 and a little breathing room. Jared Goff did his best to bring the Lions back to within a score, but Detroit could not capitalize on two onside kick attempts in the fourth quarter.

The Bills head to Detroit for a highly anticipated matchup between two of the best teams in the NFL. Buffalo is looking to rebound from their worst defensive performance since the 2021 season after their 44-42 loss to the Rams in Week 14. The Lions are on an 11-game winning streak and have overcome a rash of injuries while maintaining a one-game lead in the competitive NFC North.

The Bills came up short in a 44-42 shootout to the Los Angeles Rams, ending their seven-game winning streak and leaving them with a 12% chance at the number one seed in the AFC. The Rams started the game with a 12-play, 70-yard scoring drive, where they went 3-3 on third down with little resistance or pressure from the Bills’ defense. This drive would serve as a precursor for what we would see the rest of the game.